EP-1360: Heat shock protein 70 serum levels as a predictor of clinical response in non-small-cell lung cancer
نویسندگان
چکیده
منابع مشابه
Dynamics of Heat Shock Protein 70 Serum Levels As a Predictor of Clinical Response in Non-Small-Cell Lung Cancer and Correlation with the Hypoxia-Related Marker Osteopontin
Hypoxia mediates resistance to radio(chemo)therapy (RT) by stimulating the synthesis of hypoxia-related genes, such as osteopontin (OPN) and stress proteins, including the major stress-inducible heat shock protein 70 (Hsp70). Apart from its intracellular localization, Hsp70 is also present on the plasma membrane of viable tumor cells that actively release it in lipid vesicles with biophysical c...
متن کاملSerum heat shock protein 70 levels and lung cancer risk: a case-control study nested in a large cohort study.
Chronic inflammation contributes to the process of carcinogenesis, but few epidemiologic studies have examined associations with risk of lung cancer. Relationships between lung cancer risk and serum levels of both heat shock protein 70 (Hsp70) and high-sensitivity C-reactive protein (hsCRP) were investigated in a case-control study nested in the Japan Collaborative Cohort Study for Evaluation o...
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Introduction: Breast cancer is the most common cancer diagnosed among women worldwide. Increased molecular and genetic information about cancer has improved diagnostic, screening, and treatment methods for cancer. Heat shock protein 70 (HSP70) is overexpressed in breast cancer patients and involved in malignant properties of breast cancer. Due to the noninvasive nature of saliva collection and ...
متن کاملSerum interleukin-10 levels as a prognostic factor in advanced non-small cell lung cancer patients.
STUDY OBJECTIVE To investigate the prognostic significance of interleukin (IL)-10 serum levels in advanced non-small cell lung cancer (NSCLC) patients. DESIGN IL-10 serum levels were measured before chemotherapy, on completion of therapy, and at follow-up by means of a commercially available enzyme-linked immunoassay. The results were then analyzed in comparison with other prognostic variable...
متن کاملSerum Interleukin-10 Levels as a Prognostic Factor in Advanced Non-small Cell Lung Cancer Patients*
Study objective: To investigate the prognostic significance of interleukin (IL)-10 serum levels in advanced non-small cell lung cancer (NSCLC) patients. Design: IL-10 serum levels were measured before chemotherapy, on completion of therapy, and at follow-up by means of a commercially available enzyme-linked immunoassay. The results were then analyzed in comparison with other prognostic variable...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2018
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(18)31669-4